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Was there a placebo or control group

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New England Journal of Medicine, 375 (24), 23592370

5 Pigmented Lesions of the Oral Mucosa Alfredo Aguirre, DDS, MS Faizan Alawi, DDS Jose Luis Tapia, DDS, MS Healthy oral soft tissue presents a typical pink to red hue that reflects the degree of keratinization, quantity and activity of melanocytes, vascularization, and type of submucosal tissue of distinct topographic areas

Drug Dev Res 79(8):373382 Van Norman GA (2019) Limitations of animal studies for predicting toxicity in clinical trials: is it time to rethink our current approach